Epileptogenic Source Imaging Using Cross Frequency Coupled Signals from Scalp EEG
The epileptogenic zone (EZ) is a brain region responsible for seizure genesis. This study describes a novel EEG source imaging (ESI) method to estimate the EZ which uses cross frequency coupled potential signals (SCFC) derived from scalp EEG. Results were validated using 1) known surgical resections for Engel I-IV patients, and 2) through forward modelling with noise simulation. The SCFC demonstrated significant advantages over “raw” scalp EEG.
Spatial Coherence Profiles of Ictal High Frequency Oscillations Correspond to those of Interictal Low Frequency Oscillations in the ECoG of Epileptic Patients
With the advent of new recording techniques, fast electrical activity (>80 Hz) has become a new focus in brain research. We examined the relationship between the spatiotemporal coherence patterns of slow and fast electrical oscillations in the brains of patients with extratemporal lobe epilepsy.