3D Measurements of Acceleration-Induced Brain Deformation via Harmonic Phase Analysis and Finite-Element Models
Measuring brain deformation enables researchers to better understand traumatic brain injuries and develop methods for injury prevention. However, quantifying three-dimensional motion prevent in the intact human brain poses significant challenges. We present a new technique to estimate tissue deformation by combining data from tagged magnetic resonance images with a biomechanical model of the brain itself. This approach provides direct quantification of brain deformation from in vivo data during accelerative events that are typical of everyday activities, and provides insight into the brain’s behavior in more severe impacts.