In Vivo Magnetic Stimulation of Rat Sciatic Nerve With Centimeter- and Millimeter-Scale Solenoid Coils
Previous reports of magnetic stimulation of the peripheral nervous system (PNS) used various coil geometries, all with outer diameters larger than 35 mm, and stimulation energies in the 50 J range to evoke neural excitation. Recent reports of central nervous system (CNS) activation used sub-mm-scale solenoid coils with mJ energy levels. The goal of this study was to translate the lower energy levels from the CNS to the PNS via using smaller coils placed in closer proximity to the neural tissue.
Model-Based Analysis of Electrode Placement and Pulse Amplitutde for Hippocampal Stimulation
To support advancements in memory prosthetics, we have built a computational model to study the effects of electrical stimulation on the hippocampus. Predictions made by this model were first validated against signals obtained from real tissue samples and later used to search possible electrode placements and stimulation amplitudes for combinations that elicited the most efficient tissue response.
A μm-Scale Computational Model of Magnetic Neural Stimulation in Multifascicular Peripheral Nerves
Accurate prediction of stimulator performance in animal or human subjects is an important step in the design and optimization of coil and stimulator parameters. Currently, predictions are based on the induced electric field simulation in a homogenous tissue environment which does not account for random fascicle distributions inside the nerve and high density axon distributions inside individual fascicles.