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Krishnan Thyagarajan

Krishnan Thyagarajan is with the Palo Alto Research Center, a Xerox company, Palo Alto, CA, USA


Contributions

  • Micro-coil design influences the spatial extent of responses to intracortical magnetic stimulation
    Micro-coil Design Influences the Spatial Extent of Responses to Intracortical Magnetic Stimulation

    Magnetic stimulation from micro-coils has the potential to improve the spatial resolution of cortical stimulation by selectively activating pyramidal neurons while avoiding passing axons. Here, we explored how micro-coil design influences the effectiveness and selectivity with which neurons are activated. Computational modeling and physiological experiments revealed that the use of a sharp bend at the coil tip (V-shaped) enhanced coil selectivity; an additional bend provided even higher selectivity. The use of a second loop enhanced coil strength. Our results suggest that further optimization of coil design may help to enhance both the strength and selectivity of future coil designs.

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