Smart Cell Culture Monitoring and Drug Test Platform Using CMOS Capacitive Sensor Array
Integrated Microfluidic CMOS or imCMOS has recently received significant interest, as a new paradigm in the design and implementation of chemical/biological analysis platforms, for life science applications. Among these applications, this research has focused on developing a novel imCMOS device for monitoring drug cytotoxicity. This device incorporated with polyelectrolyte layers consists of 8×8 capacitive sensors integrated on the same chip. With the potential to perform label free cellular analysis, the proposed platform opens an avenue to transit from traditional to smart cellular analysis techniques suitable for a variety of biological applications, in particular high throughput cell based drug testing.
A Functional-genetic Scheme for Seizure Forecasting in Canine Epilepsy
Seizure prediction is currently a major concern in the epilepsy research community. In this work, we have proposed a new strategy to achieve accurate seizure forecasting by combining effective connectivity measures and artificial intelligence techniques. Results show performance improvement compared to previous studies, achieving average sensitivity of 84.82% and time in warning of 0.1.