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Shelley Irwin Fried

Shelley Irwin Fried is with the Boston VA Healthcare System, Rehabilitation, Research and Development, Boston, MA, and with the Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA


Contributions

  • Micro-coil design influences the spatial extent of responses to intracortical magnetic stimulation
    Micro-coil Design Influences the Spatial Extent of Responses to Intracortical Magnetic Stimulation

    Magnetic stimulation from micro-coils has the potential to improve the spatial resolution of cortical stimulation by selectively activating pyramidal neurons while avoiding passing axons. Here, we explored how micro-coil design influences the effectiveness and selectivity with which neurons are activated. Computational modeling and physiological experiments revealed that the use of a sharp bend at the coil tip (V-shaped) enhanced coil selectivity; an additional bend provided even higher selectivity. The use of a second loop enhanced coil strength. Our results suggest that further optimization of coil design may help to enhance both the strength and selectivity of future coil designs.

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