A New Image Similarity Metric for Improving Deformation Consistency in Graph Based Groupwise Image Registration
Image similarity metric (ISM) is used to construct the graph of input images in graph based groupwise image registration (G-GIR). Most existing G-GIR methods adopt image intensity-based ISM. However, image intensity is not directly related to deformation directions in image registration, and inconsistent deformation along the shortest paths in the resulting graph is inevitable, making G-GIR inefficient and inaccurate. We propose a new ISM to build the graph with deformation consistency. Our ISM reduces inconsistent deformation and improves registration outcome.