Restenosis remains a challenge for treatment of atherosclerosis due to damage of the vascular endothelium and induced proliferation of the smooth muscle cell. A new thermal balloon is designed to selectively ablate the atherosclerosis plaque. The volume heating of RF currents is integrated with the surface convection of the internal cooling agent to focus the thermal energy on the plaque while sparing the vascular endothelium. Microelectrodes array is designed for the conformal treatment. The numerical study clearly illustrates the heating and regulating capacity of the design for different treatment necessities. With its further development, a precision thermal treatment of atherosclerosis resistive to restenosis may be realized.