Posts Tagged: thermal ablation

  • Self-scanned HIFU ablation of moving tissue using real-time hybrid US-MR imaging

    Self-scanned HIFU ablation of moving tissue using real-time hybrid US-MR imaging

    High Intensity Focused Ultrasound (HIFU) treatment in the abdominal cavity is challenging due to the respiratory motion. In the self-scanned HIFU ablation method the focal spot is kept static and the heating pattern is obtained through natural tissue motion. A novel approach is described for compensating for the effect of tissue motion on thermal build-up, by modulating the HIFU power during self-scanning according to tissue speed, estimated by speckle tracking on ultrasound images. This method provides the first experimental validation of the self-scanning HIFU ablation paradigm via a real-time hybrid MRI/US imaging, opening the path towards self-scanning in vivo therapies.

  • Recent Advances in Thermal Treatment Techniques and Thermally Induced Immune Responses Against Cancer

    J. F. Bai, P. Liu, and L. X. Xu, Shanghai Jiao Tong University, Volume 61, Issue 5, Page:1497-1505
    Thermal ablation techniques present promising approaches to tumor treatment, and it has been recognized lately the possible of whole body immune response through thermally induced depletion of immune suppression cells and in situ release of tumor specific antigens. In this paper, recent developments of thermal ablation techniques are reviewed and compared with the emphasis on thermal energy delivery methods, thermally induced immunological responses in depth. It is suggested that the synergy of local thermal ablation and thermally induced whole body immune response could be a promising direction for effective cancer therapy in the near future, especially for highly metastatic tumor.

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