Smart Cell Culture Monitoring and Drug Test Platform Using CMOS Capacitive Sensor Array
Integrated Microfluidic CMOS or imCMOS has recently received significant interest, as a new paradigm in the design and implementation of chemical/biological analysis platforms, for life science applications. Among these applications, this research has focused on developing a novel imCMOS device for monitoring drug cytotoxicity. This device incorporated with polyelectrolyte layers consists of 8×8 capacitive sensors integrated on the same chip. With the potential to perform label free cellular analysis, the proposed platform opens an avenue to transit from traditional to smart cellular analysis techniques suitable for a variety of biological applications, in particular high throughput cell based drug testing.