Posts Tagged: photoacoustic imaging

  • Real-Time Photoacoustic Thermometry Combined with Clinical Ultrasound Imaging and High-Intensity Focused Ultrasound

    Description: High intensity focused ultrasound (HIFU) is a non-invasive method for treating diseased tissues by locally delivering thermal and mechanical energy. In HIFU, measuring the temperature at the treatment site is important for therapeutic efficacy, safety, appropriate treatment planning. In this paper, we propose a novel integrated real-time photoacoustic thermometry system for HIFU treatment monitoring that provides real-time photoacoustic and ultrasound imaging and photoacoustic thermometry without any interference from the HIFU waves. We have successfully demonstrated the feasibility of photoacoustic thermometry with in vitro phantoms and in vivo tumor-bearing mice, which promises a safe and effective monitoring of HIFU treatment.

  • Optical Detection of Ultrasound in Photoacoustic Imaging

    Optical Detection of Ultrasound in Photoacoustic Imaging

    Photoacoustic (PA) imaging offers unique capabilities in studying biological tissue based on optical absorption contrast. The sensitivity and bandwidth in detecting laser-induced ultrasonic signals are crucial for attaining high-quality and high-resolution PA images. Recent studies have shown that optical detection of ultrasound can provide improved detection angle and sensitivity over significantly extended bandwidth. In this review, we provide an overview of recent technological advances in optical methods of ultrasound detection by classifying them based on their implementations in photoacoustic imaging. We further introduce a theoretical framework to generalize sensitivity, bandwidth, and spatial responses of optical ultrasound detection geometries.

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